top of page

Maximum Potency Neat Dose

Experienced Users Only

Single Active Ingredient

Nuance Neat++ 500 mg microdose bottle

The upper boundary. For those who know.

$98         30 capsules · $3.27/dose

Lab-tested for potency & purity

Vegan · Gluten-free

GMO-free

Carbon-offset shipping

Certificate of analysis available

not a beginner product

Neat++ is designed exclusively for experienced individuals with an established relationship with psilocybin. If you're new to microdosing, we recommend starting with Neat- 50 mg or Neat 100 mg and building gradually. Set, setting, and intention matter more at this level than at any other point in the Neat range.

Where Neat++ 500 sits in the lineup

Nuance Neat Family Dose Comparison - Single Active Ingredient

why neat++ 500 mg?

🔺

The highest pure dose

500 mg is the top of the Neat range — five times Neat 100. For those who have built tolerance and want to explore the upper boundary intentionally.

🧪

SIngle active ingredient only,

P. cubensis and microcrystalline cellulose — same clean formula as every Neat product, just a larger dose in a size 000 capsule.

🔬

Independently tested

Every batch third-party verified for potency and purity. COA publicly linked on the product page — full transparency at every dose level.

🤝

Integration support included

At higher doses, community matters more. Monthly Nuance Network sessions with an integration specialist are included with every purchase.

What you may experience

A more vivid, emotionally textured quality to your dose days — richer than lower doses in the Neat range

Heightened sensory awareness or appreciation — colors, music, and nature may feel more present

A deeper sense of introspection or inward openness that invites reflection

More pronounced mood shifts — upward or inward depending on the individual and their setting

For some, 500 mg remains largely sub-perceptual. For others, it crosses into light psychedelic territory — individual sensitivity varies significantly at this level

Whos it for?

Experienced microdosers who have worked through the Neat range and want to explore the upper boundary

Those seeking a more pronounced introspective or emotionally open experience within a manageable range

Individuals familiar with their personal psilocybin sensitivity and how it affects their mind and body

People who prefer occasional, more intentional dose days rather than frequent low-dose protocols

Those exploring the space between traditional microdosing and a full macrodose — sometimes called a mini-dose or museum dose

Product specs

Dosage per capsule

500 mg P. cubensis (Fruiting Bodies)

Capsules per bottle

30 capsules

Suggested use

1–2 capsules, occcasionally

Capsule type

Vegan HPMC (size 000), preservative-free

Ingredients

P. cubensis mushrooms, Microcrystalline cellulose

Certifications

Vegan · GMO-free · Gluten-free

Nuance Network included with every purchase

Your purchase includes access to monthly 60-minute virtual group sessions led by an integration specialist. Third Sunday of each month, 10:00 AM Pacific. Community, education, and peer support — built into the price.

frequently asked questions

Is 500 mg still a microdose?

It depends on the individual. The standard microdosing range is typically cited as 50–300 mg. At 500 mg, Neat++ occupies what many in the psychedelic wellness community call a "mini-dose" or "museum dose" — the territory between a traditional microdose and a full macrodose. For some experienced users it remains sub-perceptual; for others it produces a noticeable, light shift in perception. Know your sensitivity before trying this dose level.

Should I have experience with lower doses first?

Yes — strongly recommended. We suggest working through Neat 100 mg and Neat+ 200 mg before stepping up to 500 mg. Understanding how your body and mind respond at lower doses gives you the foundation to navigate a higher dose with confidence and intention.

What schedule should I follow?

We suggest the Fadiman protocol as a baseline: 1 day on, 2 days off. At 500 mg, many experienced users prefer a more conservative schedule — every four or five days — to allow for full integration between sessions. Microdosing is highly individual — the protocol and time of administration can vary according to your lifestyle and daily requirements.

The capsule seems large — is there another way to take it?

Neat++ uses a size 000 capsule to accommodate the higher volume. If swallowing it whole is uncomfortable, simply open the capsule and mix the contents into a beverage or soft food. Alternatively, two Neat+ 200 mg capsules achieve a comparable 400 mg dose with smaller size 1 capsules.

Is this product lab tested?

Yes. Every batch is independently tested for potency and purity. The Certificate of Analysis (COA) is publicly available — linked directly on the product page.

What will I see on my credit card statement?

Charges appear as NUANCE WELLNESS for your privacy.

customer review

Three thumbs up

"I took two capsules as recommended, at a Lady Gaga concert. It was not too over the top — but enough to make the concert just a little more enjoyable."

3283.SC — Verified purchase, Jul 2025

$10 flat-rate shipping · Carbon-offset included

microdose mushroom capsules

500mg psilocybin microdose capsules

psilocybe cubensis microdose

high potency microdose supplement

step up microdose formula

two ingredient microdose

high dose microdose capsules

lab tested microdose

psilocybin wellness capsules

experienced microdosers formula

psilocybin introspection

microdose emotional resiliance

vegan mushroom supplement

experienced microdosers supplement

advanced microdose supplement

museum dose psilocybin

mini dose mushroom capsules

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Testimonials reflect individual experiences and may not represent typical results. Consult a healthcare professional if you have health concerns. Do not replace prescribed medications without consulting your doctor.

bottom of page