The Original Formula
Most Popular
Single Active Ingredient
The flagship microdose. Clean, proven, intentional.
$35 30 capsules · $1.17/dose
Lab-tested for potency & purity
Vegan · Gluten-free
GMO-free
Carbon-offset shipping
Certificate of analysis available
Where Neat 100 sits in the lineup
why neat 100 mg
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The classic threshold
100 mg sits at the heart of the standard microdosing range — meaningful enough to notice over time, subtle enough for daily life.
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Two ingredients only
P. cubensis and an inert filler. No adaptogens, no proprietary blends. A clean baseline you can trust and build from.
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Independently tested
Every batch third-party verified for potency and purity. COA linked directly on the product page — full transparency.
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Community included
Monthly Nuance Network sessions with an integration specialist. Real support, peer connection, and professional guidance — built in.
What you may experience
A subtle shift in mood or emotional openness that complements rather than interrupts your day
Increased ease of focus or creative thinking during work and problem-solving
A greater sense of calm during stressful moments without sedation
Improved presence and engagement in everyday interactions
These effects are sub-perceptual — the goal is a quiet, supportive undercurrent, not a high
Whos it for?
People who've done their research and are ready to start a structured microdosing practice
Those who want a pure, single-ingredient baseline before experimenting with stacked formulas
Anyone stepping up from Neat- 50 mg who is ready to move to the standard threshold
Individuals exploring mushroom supplementation for stress, focus, emotional resilience, or creative flow
Protocol-minded microdosers following Fadiman or similar evidence-informed schedules
Product specs
Dosage per capsule
100 mg P. cubensis (Fruiting Bodies)
Capsules per bottle
30 capsules
Suggested use
1–2 capsules every 3 days
Capsule type
Vegan HPMC (size 2), preservative-free
Ingredients
P. cubensis mushrooms, Microcrystalline cellulose
Certifications
Vegan · GMO-free · Gluten-free
Testing
Nuance Network included with every purchase
Your purchase includes access to monthly 60-minute virtual group sessions led by an integration specialist. Third Sunday of each month, 10:00 AM Pacific. Community, education, and peer support — built into the price.
frequently asked questions
Why is 100 mg the most popular starting dose?
100 mg of dried P. cubensis is widely recognized as the classic microdose threshold — sitting comfortably within the 50–300 mg sub-perceptual range most researchers and practitioners reference. It's meaningful enough to produce a noticeable undercurrent over time, but well under the level that produces any perceptual changes. Most people find it the ideal balance.
How does Neat 100 differ from Neat- 50 or Neat+ 200?
Neat 100 mg is our original, benchmark formula. Neat- 50 mg is half the dose — designed for sensitive individuals or first-timers wanting to start very gently. Neat+ 200 mg is double — suited to those who have built familiarity with 100 mg and want to step up intentionally. Neat 100 is the right starting point for most people.
What schedule should I follow?
We suggest the Fadiman protocol: 1 day on, 2 days off. Take 1–2 capsules every three days to prevent tolerance buildup and allow your nervous system time to integrate. Microdosing is highly individual — the protocol and time of administration can vary according to your lifestyle and daily requirements.
Why only two ingredients?
When you're new to microdosing — or want a reliable baseline — the last thing you need is to wonder which ingredient is doing what. A clean, two-ingredient formula gives you a clear signal. Once you know how your body responds to Neat, you can explore our stacked formulas like Dirty, Bright, Vitality, or Somnium with confidence.
Is this product lab tested?
Yes. Every batch is independently tested for potency and purity. The Certificate of Analysis (COA) is publicly available — linked directly on the product page.
What will I see on my credit card statement?
Charges appear as NUANCE WELLNESS for your privacy.
$10 flat-rate shipping · Carbon-offset included
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These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Testimonials reflect individual experiences and may not represent typical results. Consult a healthcare professional if you have health concerns. Do not replace prescribed medications without consulting your doctor.