Intentional MIcrodose Formulation
Physical performance formula
Psilocybin + Yohimbe + Ashwagandha
In your body. Energized, present, alive.
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Designed for daytime use, Dirty leans energizing for many and is intended for active, embodied experiences—not winding down. Crafted for movement and momentum, it’s often used for workouts, dancing, intimacy, trail runs, and other embodiment practices. We recommend taking it during the day to allow for a regular night's rest.
$45 30 capsules · $1.50/dose
Lab-tested for potency & purity
Vegan · Gluten-free
GMO-free
Carbon-offset shipping
Certificate of analysis available
whats inside + why it matters
Psilocybe cubensis
(Magic mushrooms)
100 mg per capsule
The psilocybin foundation found across the Nuance lineup. At 100 mg, it provides a gentle sub-perceptual base that supports emotional openness, presence, and a relaxed, curious connection to the body — ideal as the starting point for a physically focused blend.
Pausinystalia johimbe
(Yohimbe )
250 mg per capsule · organically grown
Derived from the bark of the Yohimbe tree, Yohimbe is one of the most well-known botanicals for supporting arousal, libido, and physical energy. It works by increasing blood flow and enhancing the release of norepinephrine — a neurotransmitter that stimulates physical function and drive. It's the energizing backbone of this blend.
Withania somnifera
(Ashwagandha )
100 mg per capsule · organically grown
One of Ayurveda's most revered adaptogens. Ashwagandha supports vitality and physical performance by reducing stress and balancing cortisol levels — which, when elevated, are often linked to reduced energy and drive. It also supports testosterone levels and overall physical resilience, balancing the stimulating energy of Yohimbe with grounded, sustained strength.
Important safety notes:
Ashwagandha should be used with caution if you have an autoimmune condition or are taking benzodiazepines. It may lower blood sugar levels — monitor accordingly if relevant.
Yohimbe may impact blood pressure. Consult your healthcare provider before use if you have a cardiovascular condition or are on blood pressure medication.
As with all supplements, do your own research and consult a healthcare professional for personalized advice around contraindications.
why dirty 100 mg?
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Energized embodiment
The only formula in the lineup built around physical energy and embodiment — relaxed and alive in your body at the same time.
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Libido & arousal support
Yohimbe and Ashwagandha are two of the most researched botanicals for supporting arousal, libido, and sexual vitality — paired with psilocybin's capacity for presence and openness.
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Physical performance
Users report enhanced performance across workouts, trail runs, and dance — the blend supports both the mental ease of microdosing and the physical energy of adaptogen support.
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Community included
Monthly Nuance Network sessions with an integration specialist. Education, peer support, and professional guidance — built into every purchase.
What you may experience
A relaxed, energized state — calm in the mind, activated in the body
Enhanced sense of physical presence and embodiment during movement, exercise, or intimacy
Increased arousal, drive, and libido — the synergistic effect of Yohimbe and Ashwagandha working together
Reduced stress-driven fatigue — Ashwagandha's cortisol-balancing effect supporting sustained physical energy
A heightened sense of aliveness and connection to sensory experience — one of the most commonly reported effects of this blend
Whos it for?
Those who want to deepen their connection to physical sensation and embodiment while microdosing
Active people who want a formula that supports and enhances their workout, run, or movement practice
Anyone exploring the intersection of microdosing and sexual wellness, intimacy, or libido support
People navigating stress-driven energy depletion who want adaptogen support alongside psilocybin
Those already comfortable with Neat 100 who want to explore a more physically activating formula
Product specs
P. cubensis per capsule
100 mg (Fruiting Bodies)
Yohimbe per capsule
250 mg (organically grown)
Ashwaghanda per capsule
100 mg (organically grown)
Capsules per bottle
30 capsules
Suggested use
1–2 capsules, every 3 days
Capsule type
Vegan HPMC (size 00), preservative-free
Certifications
Vegan · GMO-free · Gluten-free
Testing
Nuance Network included with every purchase
Your purchase includes access to monthly 60-minute virtual group sessions led by an integration specialist. Third Sunday of each month, 10:00 AM Pacific. Community, education, and peer support — built into the price.
frequently asked questions
What makes Dirty different from the other Nuance formulas?
Dirty is the only formula in the lineup built specifically around physical energy, embodiment, and libido support. Where Neat is a pure baseline, Vitality targets brain health, Somnium is for sleep, and Bright supports mood, Dirty pairs psilocybin with Yohimbe and Ashwagandha — two of the most researched botanicals for physical vitality and arousal. It's designed to be felt in the body, not just the mind.
Can I take Dirty before a workout?
Yes — this is one of the most common use cases reported by customers. The blend of psilocybin's mental ease with Yohimbe's physical energy and Ashwagandha's stress-buffering adaptogen support makes Dirty well-suited for movement, exercise, and physical activity. Take 1–2 capsules with enough time before your session to feel the blend settle in.
Why is it recommended as a daytime formula?
Yohimbe in particular can be energizing for some people — similar to a mild stimulant effect. Taking Dirty too late in the day may interfere with sleep onset for sensitive individuals. We recommend morning or early afternoon dosing to allow the formula to run its course before bedtime. If you want a nighttime formula, Somnium is designed for that purpose.
What schedule should I follow?
We suggest the Fadiman protocol: 1 day on, 2 days off. Take 1–2 capsules every three days during the daytime. Microdosing is highly individual — the protocol and time of administration can vary according to your lifestyle and daily requirements.
Are there any contraindications I should know about?
Yes — Ashwagandha should be used with caution if you have an autoimmune condition or take benzodiazepines, and may lower blood sugar levels. Yohimbe may impact blood pressure and should be approached carefully if you have cardiovascular concerns or are on blood pressure medication. Always consult your healthcare provider before starting any new supplement, especially if you have existing health conditions.
Is this product lab tested?
Yes. Every batch is independently tested for potency and purity. The Certificate of Analysis (COA) is publicly available and linked on the product page.
What will I see on my credit card statement?
Charges appear as NUANCE WELLNESS for your privacy.
customer review
Great energy booster!
"I enjoy taking these before a gentle workout or trail run as my mind feels relaxed and my body feels energized. Excited to try the other mushroom and herbal options!"
Eaden — Verified purchase, Dec 2025
Refocuses my body and brain
"When I am stressed I take these to refocus my energy and they work amazingly!"
Marissa — Verified purchase, Dec 2025
Dirty
"It arrived as expected and performed better than expected. Very happy!"
JK — Verified purchase, Jun 2025
$10 flat-rate shipping · Carbon-offset included
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These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Testimonials reflect individual experiences and may not represent typical results. Consult a healthcare professional if you have health concerns. Do not replace prescribed medications without consulting your doctor.